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[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Masuko K., Murata M., Yudoh K., Kato T., Nakamura H

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Senolytic therapies are often administered in an intermittent dosing paradigm composed of 2-6 cycles, each involving 1-7 days of high-dose treatment, followed by a 1-4 week rest period (off treatment), allowing for the suppression of excess cellular senescence without interfering with the basal levels and functions of senescent cells (A)